LASP1 in Cellular Signaling and Gene Expression: More than Just a Cytoskeletal Regulator
LIM and SH3 protein 1 was originally identified as a structural cytoskeletal protein with scaffolding function.However, recent data suggest additional roles in cell signaling and gene expression, especially in tumor cells.These novel functions are primarily regulated by the site-specific phosphorylation of LASP1.This review will focus on specific p